Coding
Part:BBa_K3221001:Design
Designed by: Qihan Jin Group: iGEM19_SCU-China (2019-10-01)
CNS3
Assembly Compatibility:
- 10INCOMPATIBLE WITH RFC[10]Illegal XbaI site found at 2614
Illegal SpeI site found at 1275 - 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 1303
Illegal SpeI site found at 1275 - 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 1747
- 23INCOMPATIBLE WITH RFC[23]Illegal XbaI site found at 2614
Illegal SpeI site found at 1275 - 25INCOMPATIBLE WITH RFC[25]Illegal XbaI site found at 2614
Illegal SpeI site found at 1275
Illegal AgeI site found at 2677 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
There are two domains in this parts, NK and HisG. They are relatively independent, so we can devide them by PCR.
Source
We got this part by gene synthesis. And it can also be found in the genome of Cordyceps militaris.
References
Xia Y , Luo F , Shang Y , et al. Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin[J]. Cell Chemical Biology, 2017:S2451945617303276.